Assessment Of Thyroxine Status In Patients With Chronic Kidney Disease

Abstract

Thyroid problems are common in patients with chronic kidney disease (CKD), which is becoming an increasingly important issue in public health across the world. This prospective research aimed to examine the relationship between thyroid dysfunction and the severity of renal diseases in 100 persons with CKD. Among the individuals surveyed, 60% had low T3 syndrome and 45% low T4 syndrome. Fifteen individuals also had primary hypothyroidism. The research discovered that when the glomerular filtration rate fell, there were significant variations in the frequency of individuals identified with low T3 syndrome. There was no change to the normal range in TSH levels throughout the stages of renal disease. Irrespective of the severity of their chronic illness or malnutrition, thyroid dysfunction was seen in most individuals with chronic renal impairment. As CKD promotes protein conservation, its low T3 state may actually be beneficial. Low T3 syndrome is more common in patients with advanced renal failure.